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Last updated: 08 May 2006

Seashore Foraging & Fishing Study
Early Human Diet

What is Iodine ?

Why is it important ?

What happens if you don't get enough

Who does Iodine Deficiency affect ?

Why are areas deficient in iodine ?

Sea salt doesn't help much

And nor does meat...

Agricultural staples not much good...

Why aren't we all cretins ?

Iodine in the 'Cradle of Mankind'

Iodine & the Neanderthals

HELP !!!

 

 

 

 

Iodine - The Missing Ingredient

Iodine deficiency is estimated to have lowered the intellectual capacity of almost all of the nations reviewed* by as much as 10 to 15 percentage points.

Iodine deficiency in pregnancy is causing almost 18 million babies a year to be born mentally impaired.

Vitamin & Mineral Deficiency    A Global Progress Report 

*The UN reviewed 80 developing nations, containing 80% of the world's population.

Put another way, the entire world is about 10% more stupid than it need be, due to iodine deficiency.

What is Iodine ?

Iodine, the 53rd element in the periodic table, is a key ingredient in thyroxine, a hormone produced in the thyroid gland. When a pregnant woman's diet lacks iodine, her fetus may suffer inadequate brain development because thyroxine production is inhibited. Thyroxine promotes complex brain development and thus directly affects an infant's intelligence. Although iodine is a critical nutritional supplement, very little of the substance—about 0.001 g (0.02 grain) each day—is required to prevent iodine deficiency disorder.

Microsoft Encarta 2004

The 'agreed' healthy intake rate of iodine for a human adult is 60-120mcg per day (rounded off to 100mcg as an RDV). More is required during pregnancy and lactation, and a healthy range could be from 100 to 1000mcg per day.

Why is it important ?

"Thyroid (Thyroid Gland) - The thyroid gland is an organ with many veins, anchored around the front of the throat near the voice box. It is essential to normal body growth in infancy and childhood. It absorbs iodine from the diet and releases thyroid hormones - iodine-containing compounds that help govern the rate of the body's metabolism (its total life processes), affecting body temperature, and regulating protein, fat and carbohydrate catabolism in all cells. They keep up growth hormone release, skeletal maturation, and heart rate, force, and output. They promote central nervous system growth, stimulate the making of many enzymes, and are necessary for muscle tone and vigour. To a high degree, metabolism is regulated by the hormone thyroxine, which can be made by the thyroid if enough organic iodine is available. An enlarged thyroid gland that is not cancer is sometimes called goitre"

Iodine Requirement

The total range of influence of thyroid hormones on ontogenic (individual organism) development (from early  embryonic through postnatal stages) and adult physiology in all vertebrates is truly staggering. Thyroid hormones are known to be essential for: early embryonic cell migration,  differentiation and maturation; both embryonic and postnatal growth; development of the entire central nervous system, including the eyes and brain; hair growth; adrenal gland  function; skin and hair pigment production; development and function of the gonads.

Crockford

What happens if you don't get enough of it?

Failure to have adequate iodine leads to insufficient production of the thyroid hormones, thyroxine and triiodothyronine, which affect many different parts of the body, particularly muscle, heart, liver, kidney, and the developing brain. Inadequate hormone production adversely affects these tissues, resulting in the disease states known collectively as the iodine deficiency disorders, or IDD. The consequences of iodine deficiency include:

 

Mental retardation

Other defects in development of the nervous system

Goitre (enlarged thyroid)

Physical sluggishness

Growth retardation

Reproductive failure

Increased childhood mortality

Economic stagnation

and: loss of control of the muscles of the mouth resulting in mouth contortion and drooling, defective teeth, tendency to obesity and cretinism.

The most devastating of these consequences are on the developing human brain. 

SALT IODIZATION FOR THE ELIMINATION OF IODINE DEFICIENCY

Who does Iodine Deficiency affect ?

About 1.5 billion people, or nearly one-third of the Earth's population, live in areas of iodine deficiency.

Iodine deficiency has been called the world's major cause of preventable mental retardation. Its severity can vary from mild intellectual blunting to frank cretinism, a condition that includes gross mental retardation, deaf mutism, short stature, and various other defects. In areas of severe iodine deficiency, the majority of individuals risk some degree of mental impairment. The damage to the developing brain results in individuals poorly equipped to fight disease, learn, work effectively, or reproduce satisfactorily.

SALT IODIZATION FOR THE ELIMINATION OF IODINE DEFICIENCY

Iodine deficiency disorders brought about by insufficient iodine intake during pregnancy, as and infant, or as an adult are lifelong. Minor or short-term deficiencies can be corrected by iodine supplementation, but once physical damage to the brain or thyroid gland has progressed too far, it cannot be put right.

Why are some areas deficient in iodine ?

Iodine and its usual compounds are very soluble in water. Floods, fluctuating lake and river levels, melting snow, glaciation of large areas, or run-off from rain storms can all leach iodine out of the soil.

Soils from mountain ranges, such as the Himalayas, Alps, and Andes, and from areas with frequent flooding, are particularly likely to be iodine deficient. The problem is aggravated by accelerated deforestation and soil erosion. This deficiency in the soil cannot be corrected. The food grown in iodine deficient regions can never provide enough iodine to the population and livestock living there. Many other areas of the world also harbour severe iodine deficiency, such as large parts of central Africa. Living on the sea coast does not guarantee iodine sufficiency, and significant pockets of iodine deficiency have been reported from the Azores, Bombay, Bangkok and Manila for example.

SALT IODIZATION FOR THE ELIMINATION OF IODINE DEFICIENCY

Before the 20th century, significant iodine intake was largely related to the consumption of saltwater products (e.g. fish and seaweed). For example, one study showed that saltwater fish have a mean iodine concentration of 832 mcg/kg, whereas freshwater fish have a mean iodine concentration of 30 mcg/kg. This contrast in iodine content reflects the fact that the oceans are one of the largest reservoirs of iodine.

Over time, the earth's weather patterns have stripped the soils and geological strata of much iodine. The majority of this iodine run-off has collected in the oceans. Because of this, societies that have lived near bodies of saltwater, and consequently had saltwater products as mainstays in their diets, have typically had better iodine nutrition status than populations living inland.

Some iodine is fed back into the soils and surface waters due to rainfall from weather systems that gather their moisture from evaporating seawater. However, this re-supply of iodine is not significant enough to produce a variety of grains, vegetables, fruits, and grazing fauna that are rich in bio-available iodine--even in coastal areas.

Iodine & pregnancy

The vast majority of the world's available iodine is now dissolved in the sea. The only major transfer back to land (except by diet) is via methyl iodide, a trace gas produced by oceanic plankton, often far out in the oceanic 'deserts'. See: Healing Gaia - James Lovelock

Areas affected by iodine deficiency are therefore fairly predictable: 

One of the most spectacular effects of iodine and thyroid hormones happens to the axolotl, a salamander living in inland lakes in the Valley of Mexico, a typically iodine deficient area. It can breed in spite of being an overgrown tadpole larva, but with thyroid extract or iodine in the water, can mature as  a salamander. It was only 75 years after it was known as a species that some live specimens suddenly matured into something a lot less weird in a Paris museum. 

  • Far from the sea

  • Washed continuously (tropical forests) or even only occasionally (deserts and savannahs) by heavy rains with rapid run-off

  • Glaciated periodically over a couple of million years (much of Northern Europe and North America)

  • Mountain ranges or other well-drained areas


Adapted from Micronutrients Panda

Looking at the bright side.....

"Iodine has the advantage of long term storage in the human body (similar to Vitamin A) so that if supplementation is used, it only needs to be given a few times a year".

Micronutrients Panda

Which contrasts totally with other information, stating that there is no natural means of preventing urinary excretion of mineral iodine, although 'excess' iodine is stored in the thyroid as iodotyrosines, bound to proteins called thyroglobulins.

This suggests that a one-time abundance of iodine in the local diet meant that to acquire a means of keeping it had no survival value, or other evolutionary advantage, at the time. Other mammals haven't developed iodine retention mechanisms either, but then they don't have advanced mental structures and powers to maintain.

And nowadays we get a lot of our iodine only by 'accident'

"While there are no cereals or grains that naturally have high enough levels of iodine to significantly increase dietary intake, some cereal or grain products have become foundational sources of iodine for certain people groups. The addition of iodate as a stabilizer to baked goods (particularly bread), the use of the food colouring erythrosine in cereals, and the use of iodized salt in baked goods and cereals are the primary ways that iodine can find its way into these products. While the bio-availability of the iodine in erythrosine is questionable, cereal products contribute 14% of British iodine intake (30 mcg/day).

The poultry industry is aware of the importance of iodine for reproductive success, among other benefits. In the poultry industry it is common to use fish meal or seaweed in animal feed and to sterilize drinking water with iodine. The consumption of eggs in Denmark is responsible for 10% of the average daily iodine intake. Individual eggs have been shown to have as little as 13 mcg of iodine and as much as 170 mcg, reflecting the amount of iodine in the animals' diets.

Cattle raised for slaughter are treated with EDDI and given iodine-fortified feed and salt licks.  Milk products are often 'contaminated' with iodine used in the milking machine sterilisation processes."

Iodine & pregnancy

Farmers don't get paid until their animals arrive healthily at the market. Food manufacturers get paid as soon as you buy the can or package of the stuff they purvey. Work it out for yourself.

Sea salt doesn't help much

"A major portion of salt produced in the world is from sea water. Sea water contains iodine in addition to salt. However, when sea water evaporates, much of the iodine either remains in solution or is lost by evaporation. Only a small portion of the iodine is retained in the salt. Fisher and L'Abbe (1980) tested non-iodized sea salt and iodized table salt and sea salt.  The authors found 52.9 - 84.6 micrograms iodine/gram of salt in iodized salt and 1.2 - 1.4 micrograms iodine/gram in non-iodized sea salt."  

Iodine in non-iodized sea salt

And nor does meat...

"Because iodine is not concentrated in muscle tissue, meat is generally not the primary source of dietary iodine for a population. One study found 2 mcg/kg of iodine in meat products, while another study found 260 mcg/kg. Once again, this disparity is due to the iodine content of the animals' diet." 

Iodine & pregnancy

Note: the iodine content of meat is about 1000th as much as in non-iodised sea salt (lower level) or, at most, a fifth of that, found in a modern drugged meat animal.

And it's possible to get too much of a good thing....

"Seafood products are among the richest sources of dietary iodine. In a British study, (Lee SM, Lewis J, Buss DH. Iodine in British foods and diets. British Journal of Nutrition (1994). 72: 435-446) the iodine content in fish and shellfish (not necessarily fresh) ranged from 110 mcg/kg to 3,280 mcg/kg. In the same study, various seaweed products ranged from 4,300 mcg/kg to 2,660,000 mcg/kg. Consistent daily intake of iodine in amounts upwards of 1,000 - 2,000 mcg/day is probably detrimental to the thyroid gland's ability to process and distribute iodine to the rest of the body." 

 Iodine & pregnancy

Adults should consume about 150 mcg/day of iodine - but, if you eat 10 times as much, expect problems.

Some marine communities in Japan and Korea, subsisting on diets ultra-high in seaweed and fish, have been diagnosed with thyroid problems - hyperthyroidism - due to excess intake of iodine.

And agricultural staple foods haven't done much good...

Goitrogens - Some otherwise healthful foods contain goitrogens - substances which can interfere with iodine uptake or hormone release from the thyroid gland. These foods are generally only a concern if iodine intake is low - which the case in many poorer inland areas of the world.. 

Brassicas - cabbage, Brussels sprouts, broccoli and cauliflower, especially if consumed raw. 

Rapeseed (Canola Oil)

Apricots

Cherries

Almonds

Raw flaxseed

Certain foods are staples in many inland continental areas in Africa, South America, and Asia - precisely where iodine deficiency is already high:

Cassava

Millet

Sweet potatoes

Maize

Lima beans

Soybeans

Sorghum

The villains in this case are flavinoids. Some flavinoids are converted by the gut into the goitrogen thiocyanate, a substance that interferes with normal thyroid hormone function via competitive exclusion (thiocyanate has a similar three-dimensional molecular structure to thyroxine).

Crockford

Cassava also contains cyanide. Almost one-quarter of a billion people in the tropics consume cassava on a daily basis. Young roots may have one-third starch by weight but very little protein or fat.

Food preparation and illness

But other flavinoids, such as quercetin, an antioxidant (phytochemical) found in onions, helps eliminate free radicals in the body, inhibits low-density lipoprotein oxidation, protects and regenerates vitamin E, and helps to circumvent the harmful effects of heavy metal ions. In other words, it's bloody good for you.

Burgers 'n Fries - Onion.

The serious iodine deficiency problem in Kenya, and East Africa generally, may, in fact, be a modern one.

The high consumption of maize, cassava, sorghum, and sweet potatoes by subsistence farmers my be exacerbating the probable local shortage of iodine in the environment.

Howver, it is possible, because of the continuous volcanic and tectonic activity in the Rift Valley, that some Rift Valley lakes (and their fauna and flora) concentrate iodine, much as they concentrate other minerals.

If some lakes can concentrate enough mineral pigments in diatoms to turn flamingoes pink, why shouldn't they also accumulate iodine? As far as I know, nobody has studied this.

However, it would still be necessary, to counter the iodine problem, to eat, directly, lake shore foods, fish and shellfish, from mineral-rich lakes. Freshwater fish and shellfish don't, regrettably, live very much in mineral-rich lake water.

Humans have no instinctive urge for iodine, just as they have none for salt. We like salt, generally, but only as a condiment. We don't hunt out salt licks, even though we lose it copiously in sweat. 

In the Philippines, the major staple is unsalted, boiled rice, or cassava, a tuber  introduced from South America, for those too poor to buy or grow their own rice. 

On the coast, where the majority of Filipinos live, the vital iodine is provided by fish, shellfish, and seaweed, but those unfortunates, the original hunter-gatherers in the islands, the Aeta and Mamanwa, who have been driven into the mountains by incoming farmers and fishermen, have virtually no iodine in their diet, and it shows. The mountain Mamanwa of Mindanao are stunted, and visibly mentally deficient. 

The few remaining coastal Mamanwa, the Dumagats, are quite different. I have heard of a local Mamanwa datu, or chief, who is seven feet tall.

Why aren't North Americans and Europeans affected by iodine deficiency ? 

Why aren't they all cretins ?

Well, some of them are, of course, especially in the field of politics, but you no longer see the village idiot in every hamlet, or many like the banjo boy in the film 'Resurrection' in the hillbilly mountains of America. 

But:

Hollowell et al. (2002) tested over 17 000 Americans for serum TSH, T and thyroid antibody levels. Extrapolation of their survey results predicted that within the US alone more than 8,000,000 people unknowingly have laboratory evidence of hypothyroidism and that approximately 700,000 people unknowingly have hyperthyroidism.

Crockford

The reason for these 'low' figures is that salt iodisation has been mandatory in most of these countries over the past 60 years, and WHO is campaigning for its adoption worldwide. 

In the US, iodised salt is widely used and some other foods are fortified with iodine. In Canada all table salt is iodised. The UK has no iodine fortification strategy for plant foods or salt.

The World Summit for Children held in New York in September 1990, called for the virtual elimination of iodine deficiency disorders by the year 2000. (It hasn't been achieved yet; the world's most powerful leaders have cut the funds available for such programmes). Coincidentally, some of the most egregious of those leaders hail from inland continental areas notoriously deficient in iodine. While it would be invidious to name them, I am sure you can think of some who come from Texas or Arkansas.

Salt is a perfect medium - The cost of iodization is low: normally in the range 2-7 US cents per kilogram, which is less than 5% of the retail price of salt in most countries.  Since iodine is required in very minute quantities of the order of 150 -200 micrograms per person per day, the dosage of iodine in salt is extremely small. Salt consumption could be anywhere in the range 5 - 20 grams a day within a given region or country. 

The policy has been so successful that the iodine deficiency problem has been all but solved in most developed countries. 

SALT IODIZATION FOR THE ELIMINATION OF IODINE DEFICIENCY

It is so little of a problem now that the US Department o Agriculture, compilers of the most detailed diet analyses of all, don't even mention iodine as an essential mineral.

See HELP!

But what do you do about those who are too poor or too isolated to buy a luxury like iodised table salt, that may cost far more than local sea salt or rock salt ?

Within one year of iodized salt containing the required concentration of iodine becoming widely available and consumed in a community, there will be no further birth of cretins or children with subnormal mental and physical development attributable to iodine deficiency. Goitres, in primary school children and young adults, will have started to shrink and even disappear altogether. Children will be more active and perform better at school. Further enlargement of the thyroid in adults will be prevented.

SALT IODIZATION FOR THE ELIMINATION OF IODINE DEFICIENCY

How did iodine fit into early hominid diets ?

Not very well, it would seem:

Iodine in the 'Cradle of Mankind'

Central Africa, including the western parts of East Africa, is a notorious area of iodine deficiency.

Microsoft Encarta

Kenya: Evidence from different regions of the country suggests the presence of iodine deficiency disorders (IDD) in the country, especially in the highlands, east and west of the Rift valley. Based on several small studies, the estimated goiter rate is 7%, although the prevalence rate in the endemic regions is much higher. Goiter prevalence of 16% has been reported in pregnant women and school-age girls.

No recent large-scale studies of IDD in Kenya have been done, but the estimated goiter prevalence based on small surveys is 7%.

High goiter rates (15-72%) were reported in the early 1960s, with the highest rates in the highlands of the Rift Valley, as well as in Nyanza and Western Provinces.

Estimates based on urinary iodine excretion have indicated that 63% of the population of Kenya is at risk.

OMNI Micronutrient Fact Sheets: Kenya

Goitre, as shown in this Kenyan woman, is caused by the thyroid gland actually working harder during iodine deficiency, thus enlarging it.

And this in a country where salt iodisation has been mandatory for 35 years, since 1970. The reason for the problem is that many of the population are subsistence farmers or herdsmen, and even shop-bought iodised salt may be considered an expensive luxury, compared with 'home-made' salt made by boiling salty plants or sun-drying lake salt. It may also be due, in modern times, to staple foods being reduced to large amounts of goitrogenic plant foods like maize and cassava.

The very area where Early Hominids are said to have evolved larger and more intelligent brains has an ongoing iodine deficiency problem.

It might have been difficult for them to advance mentally in an area where the very soil is so iodine deficient that even today, with a conscious policy of iodine supplementation, there is still a goitre rate of 20% or more. 

  • So perhaps most of them were somewhere else when they developed their brains so extraordinarily.

Iodine & the Neanderthals

skull

Iodine deficient?

In 1998, Jerome Dobson published his take on the controversial Neanderthals of Europe, the direct predecessors of modern Homo sapiens sapiens. He proposes that the peculiar anatomy of Neanderthals was due to a high degree of cretinism brought about by iodine starvation, in inland areas, leached of minerals by glacial run-off.

The Iodine Factor in Health & Evolution - Geographical Review - January 1998 (Available as pdf on Internet)

His argument is compelling. As a professional scientist, though not a palaeanthropologist, he has combined the professional opinions of PAs and medical experts (although there are not many experts on cretinism nowadays, since the disease has been largely 'cured' by iodine supplementation).

This map was taken directly from Dobson's pdf article, and is therefore not too readable. I have simplified it for clarity only. He also showed  other correspondences, in the distribution of Venus  figurines, that  just didn't show up on the map.

Dobson is careful to note that maybe not all Neanderthals might have been cretins - just many of the ones whose bodily remains have been found, mainly in caves. He notes the unintentional bias inherent in finding remains only in caves. Cretins, ultra-sensitive to cold, would favour such shelters.

We frankly don't know what the others looked like - the inference is that they made the prevailing type of Mousterian stone tools found everywhere in this period - but that was upset when Neanderthal remains were found with new-style Chatelperronian tools at St-Cesaire. It was upset again when Truly Modern Human remains were found almost preceding those of Neanderthals in Skhul and Qafzeh caves in Palestine.

Which is a question never satisfactorily answered in the usual European prehistory accounts - Neanderthals are supposed to have occupied the continent exclusively for nearly ¼ million years - what happened to the 'archaic H. sapiens' who came before them? Why did the Neanderthals suddenly become 'extinct' when modern Aurignacians turned up?

Wild boar - Spanish Cave Painting

Dobson tellingly contrasts the medical diagnoses of surgeons with sculptured representations by early humans about 25-30Kya. If their animal representations are so accurate and well-observed, shouldn't their human representations be also ?

If you didn't know that this little lady was about 25,000 years old, you might well think she was just a cartoon figure from any seashore postcard, complete with bathing cap.

But there was some reason for making her statuette, and Jerome Dobson thinks that obese cretinous women were revered in Upper Palaeolithic times. Perhaps he's right.

 

 

The Venus of Willendorf  

And compares descriptions by:

Doctors

of Cretins

PAs

of Neanderthals

I have removed his references - it's up to you to find out which is which by reading his excellent paper.

 

Dobson also illustrates direct comparisons between the long bones of modern humans, Neanderthals and pathologically extreme cretins. 

The fact that a predecessor published a similar diagram 80 years ago and suffered the name of Finkbeiner should not lessen the value of his insight.

HELP !!!

Modern diets have been so buggered about by iodised salt, iodate bread improvers, iodised meat animals, and so on, that iodine is no longer a critical item (or not, at least, considered so in 'developed' countries with much 'industrialised' food). 

So there are no reliable iodine content tables around, showing what is in the original foods. Even the excellent nutrition charts produced by the US Department of Agriculture don't even mention the stuff.

The best I can offer is:

IODINE CONTENT OF SOME FOODS

FOOD

IODINE CONTENT
(micrograms per 100 grams of food)

Salt (iodized)
Seafood
Vegetables
Meat
Eggs
Dairy products
Bread and cereals
Fruits

3000
66
32
26
26
13
10
4

Healthy Eating Club - Australia

If anyone out there can point me to a reliable and accurate  iodine content in foods table, I would be very grateful

And the best I can do (at present) on where iodine comes from is this:

Origin

Iodine quantity in tons

Earth interior

600.000.000.000.000

Earth's crust counted on

2.300.000.000.000

On the continents

20 Km thickness

4.600.000.000.000

Under the seas

Earth's crust counted on 1 Km thickness

115.000.000.000

Seas and oceans

2.700.000.000

 

 

Atmospheric layer

340.000

Collieries

600.000

Recoverable iodine reserve in the saltpetre layers

600.000

Iodine Sources

Iodine follows a cycle to the sphere surface which we cannot better specify than by quoting some lines extracted the L.M. Bernard (1939) work: "atmospheric iodine and telluric iodine, fixed by the plants, are assimilated by the organized beings. These beings final decomposition releases then the metalloid. Pulled by streaming waters, it is rejected towards the seas. The sea plants absorb it and concentrate it in their cells. From sea plants, iodine goes into the fishes and shellfishes organisms. By to their disappearance and to their precipitation at the sea-bed, all and sundry form the sedimentary grounds of which high content in iodine.....a(s) highlighted by K Scharrer ".

Which is about as good as you'll get.

New Pages as at May 2006

Skull & Bones Club  Oldest Beads Were Sea Shells
Brain Development The Indo-Pacific Shoreline Ecotone
Fats & The Brain 1 - Why DHA matters African Lakes & Rivers
Fats & The Brain 2 - Born Fat Shoreline Mammals
Iodine - Missing Ingredient Shoreline Reptiles
Iodine - Evolution's Catalyst Shoreline Diet - Evidence?
Coconut Origins Shell Middens & Fish Bones
'Eco-Friendly' Poisons Insects as Food
Two unfortunate experiences of Filipino culture:
Perfectly Normal Burglary Fishing Expedition

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Richard Parker  - Siargao Island - November 2005  (Last updated Monday, May 08, 2006)  

I welcome comments or corrections on my site and opinions, so please feel free to email me at:  richardparker01@yahoo.com